The most effective anti-inflammatory agent is cannabidiol
The use of plant cannabidiol as one of the main
ingredients of cannabinoid food products, cosmetic or pharmaceutical
preparations, topical agents or various types of additives is one of the most
promising areas of development of modern hemp cultivation .
German scientists have shed light on how therapeutically active substances produced by the hemp plant can reduce inflammation in the body. They tested eight different cannabinoids and published the results of their experiments in the journal Cell Chemical Biology under the title “Cannabidiol acts as a molecular switch in innate immune cells, promoting the biosynthesis of lipid mediators that resolve inflammation.”

It was already known from previously published materials that therapeutically active hemp components have not only an analgesic and antispasmodic effect, but also an anti-inflammatory effect on the human body. Scientists from Friedrich Schiller University studied how certain components of the hemp plant fight various types of inflammation in the body.

During the experiments, German scientists learned how
various cannabinoids interact with human immune cells. According to the
results, all eight cannabinoids studied have an anti-inflammatory effect.
CBD Activates an Enzyme That
Fights Inflammation
Co-author of the study, Lukas Peltner, states that “All the
compounds we studied seem to inhibit (suppress) the formation of
pro-inflammatory messenger substances in cells, while simultaneously promoting
the formation of components that dissolve inflammation.” At the same time,
cannabidiol turned out to be the most effective therapeutic agent used to treat
various types of inflammatory processes. During the experiments, it was
determined that CBD activates the enzyme 15-lipoxygenase-1, which triggers the
production of mediators that eliminate inflammation, which then provide a
significant reduction in the course of the disease.
Another co-author of the study, Dr. Paul Mike Jordan,
explains, "Cannabidiol causes a switch in the affected cells that directs
the inflammatory process from the stimulatory side to the inhibitory
side."
Commentary from experts of the Association
“Ukrainian Industrial Hemp”
The hemp plant and its bioactive ingredients have been used since ancient times to relieve various types of inflammatory processes. Cannabinoids are recognized anti-inflammatory agents with an ever-growing popularity for the treatment of various diseases, including those associated with inflammation. Given the effectiveness of natural cannabinoids, special attention should be paid to CBD as an effective anti-inflammatory agent. Most likely, the use of plant cannabidiol as one of the main ingredients of cannabinoid food products, cosmetics or pharmacological preparations, topical agents or various types of additives is one of the most promising areas for the development of modern hemp cultivation .

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